Textbook of Pediatric HIV Care |
---|
Attached file: |
(Russian, 172 kb)
Cover
|
Attached file: |
(Russian, 136.6 kb)
Table of Contents
|
Attached file: |
(Russian, 788.1 kb)
Chapter 1. Normal development and physiology of the immune system
|
Attached file: |
(Russian, 1271.9 kb)
Chapter 2. HIV basic virology for clinicians
|
Attached file: |
(Russian, 847.7 kb)
Chapter 3. The immunology of pediatric HIV disease
|
Attached file: |
(Russian, 698.7 kb)
Chapter 4.The clinical virology of pediatric HIV disease
|
Attached file: |
(Russian, 750.2 kb)
Chapter 5.The natural history of pediatric HIV disease
|
Attached file: |
(Russian, 780.7 kb)
Chapter 6.The epidemiology of pediatric HIV disease
|
Attached file: |
(Russian, 612.9 kb)
Chapter 7.Diagnosis of HIV-1 infection in children
|
Attached file: |
(Russian, 954.4 kb)
Chapter 8.Prevention of mother-to-child transmission of HIV
|
Attached file: |
(Russian, 658.1 kb)
Chapter 9.Routine pediatric care
|
Attached file: |
(Russian, 463.1 kb)
Chapter 10. Immunizations
|
Attached file: |
(Russian, 719.1 kb)
Chapter 11.Prevention of opportunistic infections and other infectious complications of HIV in children
|
Attached file: |
(Russian, 678 kb)
Chapter 12.Emergency evaluation and care
|
Attached file: |
(Russian, 463 kb)
Chapter 13. Adherence to antiretroviral therapy in children and youth
|
Attached file: |
(Russian, 417.8 kb)
Chapter 14. Adolescents and HIV
|
Attached file: |
(Russian, 899.3 kb)
Chapter 15.Adolescent reproductive health and HIV
|
Attached file: |
(Russian, 843.9 kb)
Chapter 16.Growth, nutrition, and metabolism
|
Attached file: |
(Russian, 646.4 kb)
Chapter 17. Neurobehavioral function and assessment of children and adolescents with HIV-1 infection
|
Attached file: |
(Russian, 678.5 kb)
Chapter 18.Antiretroviral therapy
|
Attached file: |
(Russian, 728.3 kb)
Chapter 19.Antiretroviral drug interactions
|
Attached file: |
(Russian, 1169.4 kb)
Chapter 21.HIV drug resistance
|
Attached file: |
(Russian, 849.6 kb)
Chapter 22.Initiating and changing antiretroviral therapy
|
Attached file: |
(Russian, 578.4 kb)
Chapter 26. Neurologic problems
|
Attached file: |
(Russian, 1710.2 kb)
Chapter 27. Ophthalmic problems
|
Attached file: |
(Russian, 2942.3 kb)
Chapter 31. Pulmonary problems
|
Attached file: |
(Russian, 627.4 kb)
Chapter 33. Gastrointestinal disorders
|
Attached file: |
(Russian, 748.1 kb)
Chapter 37. Serious infections caused by typical bacteria
|
Attached file: |
(Russian, 539.6 kb)
Chapter 38. Tuberculosis
|
Attached file: |
(Russian, 540.5 kb)
Chapter 39. DisseminatedMycobacterium avium complex infection
|
Attached file: |
(Russian, 1302.9 kb)
Chapter 40. Fungal infections
|
Attached file: |
(Russian, 524.3 kb)
Chapter 41. Herpesvirus infections
|
Attached file: |
(Russian, 1480.2 kb)
Chapter 42. Pneumocystis carinii pneumonia (PCP)
|
Attached file: |
(Russian, 586.7 kb)
Chapter 46. Disclosure
|
Link to document(s) | http://www.cambridge.org/uk... |
Author(s): |
S. Zeichner and J. Read |
Description: |
This comprehensive textbook provides the definitive account of effective care for pediatric HIV patients. |
Language: |
Russian |
Primary area(s) of focus: |
HIV/AIDS |
Pages: |
784 |
Candidiasis and HIV |
---|
Attached file: |
(Russian, 572.4 kb)
Candidiasis and HIV
|
Link to document(s) | http://hivinsite.ucsf.edu/I... |
Author(s): |
C. J. Fichtenbaum, J. A. Aberg. |
Description: |
Mucocutaneous candidiasis occurs in 3 forms in persons with HIV infection: oropharyngeal, esophageal, and vulvovaginal disease. Oropharyngeal candidiasis (OPC) was among the initial manifestations of HIV-induced immunodeficiency to be recognized and typically affects the majority of persons with advanced untreated HIV infection. Presenting months or years before more severe opportunistic illnesses, OPC may be a sentinel event indicating the presence or progression of HIV disease. Although usually not associated with severe morbidity, OPC can be clinically significant. Severe OPC can interfere with the administration of medications and adequate nutritional intake, and may spread to the esophagus. Esophageal candidiasis remains one of the most common opportunistic infections in countries where combination antiretroviral therapy (ART) is a routine part of the standard of care. Vulvovaginal candidiasis is an important concern for women with HIV infection, although the relationship of vulvovaginal candidiasis to HIV infection remains unclear. In resource-poor nations, mucocutaneous candidiasis is a formidable problem. Despite the frequency of mucosal disease, disseminated or invasive infections with Candida and related yeasts are surprisingly uncommon. |
Language: |
English, Russian |
Primary area(s) of focus: |
HIV/AIDS, Tuberculosis |
Pages: |
39 |
Initiating Antiretroviral Therapy |
---|
Attached file: |
(Russian, 398.4 kb)
Initiating Antiretroviral Therapy
|
Link to document(s) | http://www.hivinsite.com/In... |
Author(s): |
E. M. Kojic, C.J. Carpenter |
Description: |
Combination antiretroviral regimens have revolutionized the treatment of HIV infection, which has resulted in dramatic reductions in morbidity, mortality, and health care utilization. Effective antiretroviral therapy (ART) consistently results in sustained suppression of HIV-1 RNA replication, resulting in gradual increases in CD4 T-lymphocyte count, sometimes to normal levels. ART does not eradicate the virus, as viral replication continues in lymphoid tissue despite suppressive treatment. However, durable suppression of viral replication and the accompanying increases in CD4 count, reverse HIV disease progression, even in persons with advanced HIV infection. It is now possible to achieve at least transient reversal of disease progression in almost all patients who have received no prior ART, as HIV strains present in these "treatment-naive" patients will be susceptible to available antiretroviral drugs. |
Language: |
English, Russian |
Primary area(s) of focus: |
HIV/AIDS |
Immunopathogenesis of HIV Infection |
---|
Attached file: |
(Russian, 539.4 kb)
Immunopathogenesis of HIV Infection
|
Link to document(s) | http://www.hivinsite.com/In... |
Author(s): |
M. M. Lederman, B. Rodriguez, S. Sieg. |
Description: |
As intracellular parasites, all viruses must be intimately familiar with host cellular machinery and capable of suborning it to support their replication cycle. For HIV, this relationship is particularly complex and intimate because HIV targets, infects, and incapacitates cells central to antimicrobial defenses. Thus, host immune defenses and HIV pathogenesis are inextricably linked. Whereas this parasitic relationship may contribute to the persistence and progression of HIV infection, careful study of the relationship between HIV and the immune system has also yielded important insights into mechanisms of immune homeostasis and host defenses in general. This chapter will examine briefly the proposed mechanisms whereby HIV infects host immune cells, the mechanisms whereby host defenses are mobilized to attenuate HIV replication, the strategies HIV uses to evade host immune responses, and finally, the mechanisms whereby HIV induces immune deficiency that places persons at risk for the opportunistic infections and malignancies that define AIDS. |
Language: |
English, Russian |
Primary area(s) of focus: |
HIV/AIDS |
Pages: |
38 |
Adherence to HIV Antiretroviral Therapy |
---|
Attached file: |
(Russian, 699.3 kb)
Adherence to HIV Antiretroviral Therapy
|
Link to document(s) | http://www.hivinsite.com/In... |
Author(s): |
E. L. Machtinger, D. R. Bangsberg. |
Description: |
In countries with broad access to effective antiretroviral therapy (ART), the clinical benefits have been dramatic. Far fewer people are progressing to AIDS, hospital AIDS wards have practically emptied, and the age-adjusted death rate from HIV/AIDS has declined by more than 70%.Adherence to ART has emerged as both the major determinant and the Achilles' heel of this success. Antiretroviral adherence is the second strongest predictor of progression to AIDS and death, after CD4 count. Incomplete adherence to ART, however, is common in all groups of treated individuals. The average rate of adherence to ART is approximately 70%, despite the fact that long-term viral suppression requires near-perfect adherence. The resulting virologic failure diminishes the potential for long-term clinical success. Drug-resistant strains of HIV selected through ongoing replication in the presence of ART also can be transmitted to uninfected or drug-naive patients, leaving them with fewer treatment options.Nonadherence may eventually undermine the dramatic improvements in HIV-related health parameters seen in resource-rich countries and expected in developing countries as ART becomes more widely available. |
Language: |
English, Russian |
Primary area(s) of focus: |
HIV/AIDS |
Pages: |
52 |
Clinical Characteristics of Kaposi Sarcoma |
---|
Attached file: |
(Russian, 434.2 kb)
Clinical Characteristics of Kaposi Sarcoma
|
Link to document(s) | http://www.hivinsite.com/In... |
Author(s): |
Krown S. E. |
Description: |
Kaposi sarcoma (KS) was one of the first conditions recognized as an opportunistic sequela of HIV infection, and remains the most common AIDS-associated neoplasm. AIDS-associated KS occurs with increased frequency in all HIV transmission groups compared with the general population, but at a particularly high rate among men who have sex with men (MSM). The epidemiology of AIDS-associated KS has long suggested that an environmental or infectious sexually transmitted cofactor might contribute to the development of KS. The search for such a cofactor led, in 1994, to the discovery of a novel herpesvirus, human herpesvirus-8 (HHV-8), also known as the Kaposi sarcoma-associated herpesvirus (KSHV). HHV-8/KSHV is found in all forms of KS, and infection with the virus appears to be necessary but not sufficient for KS to develop. Other factors believed to be involved in the development of AIDS-associated KS include altered expression and response to growth factors and cytokines, and modulation of KS growth by an HIV gene product, the Tat protein. AIDS-associated KS varies in its presentation from an indolent process with minimal clinical consequences to a disseminated, aggressive disease. |
Language: |
Russian |
Primary area(s) of focus: |
HIV/AIDS |
Pages: |
18 |